Groundbreaking Cambridge research indicates immunosuppression may help treat Parkinson’s
A pioneering trial, led from Cambridge Biomedical Research Centre, has shown that immunosuppressing medicines could provide the key to treatment of Parkinson's disease, according to results presented this weekend at the world's most prestigious neurodegeneration conference AD/PD
The AZA/PD trial which was carried out at the NIHR Cambridge Clinical Research Facility is the first show that broadly suppressing the immune system could have a beneficial impact in Parkinson's disease.
Participants on the treatment reported an overall improvement in movement-related symptoms. This means they found it easier to perform tasks such as moving around, writing, washing and dressing.
These improvements were greater in female participants compared to males.
Additionally, patients with faster-progressing Parkinson's disease showed signs of improved memory and thinking skills. Importantly, the trial did not reveal significant safety concerns around using immunosuppression treatment in Parkinson's disease. This will enable larger research studies of immune therapies for PD in the future.
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