Neuroscience trials

Huntington's disease (HD) is a rare genetic disease characterised by problems with movement, mood, and thinking/memory. In addition to these symptoms, around 90% of people with HD also have difficulty staying asleep during the night. Many HD gene…

Leber Hereditary Optic Neuropathy (LHON) is a rare, inherited form of vision loss. Treatment options for vision loss from LHON remain limited and no therapies aimed at reversal of the defect are available. …

Frontotemporal dementia (FTD), semantic primary progressive aphasia (svPPA, also known as semantic dementia), progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are all caused by the brain disease frontotemporal lobar…

Too much inflammation in the brain is thought to worsen recovery after a head injury, and we think that reducing inflammation might improve patients' outcomes. This study is looking to understand whether treatment with an anti-inflammatory…