Cancer trials

Trials open to recruitment

ATRiUM

AZD6738 is a potent, selective inhibitor of the serine (Ser)/threonine (Thr)-specific protein kinase, ataxia telangiectasia and Rad3-related protein (ATR), with good selectivity against other phosphatidylinositol 3-kinase-related kinase (PIKK)…

COMET20d

COVID-19 targets the body's respiratory system, where infections can be found in the nose, throat and lungs. The effect of COVID-19 infection is very variable, where many people might not know that they have been infected and have recovered from…

DIRECT

This study focuses on a form of blood cancer called lymphoma, the most common subtype of which is Diffuse Large B Cell Lymphoma (DLBCL). DLBCL is curable with chemotherapy in approximately 60% of patients. However, 40% of patients either fail to…

LUCID

Taking as reference tumour-specific somatic genetic alterations identified within individual cancer biopsies from patients, recent advances in genomic and next generation sequencing technologies now provide the opportunity to investigate whether…

Neo-RT

Four in 10 women diagnosed with breast cancer undergo mastectomy with or without breast reconstruction and less than half are satisfied with how they look unclothed. Breast conservation (removing the area with the lump only) can offer less…

PARTNER

Breast cancer is the most common female cancer worldwide, and the second most common cancer overall, with more than 1,676,000 newly diagnosed in 2012 (25% of female cancer cases and 12% of the total). Although advances in screening, surgical…

PIONEER

Breast cancer is the most common cancer in women worldwide, and the second most common cancer overall, with more than 1,676,000 people newly diagnosed in 2012 (25% of all female cancer cases and 12% of the total). Although advances in screening,…

PRaM-GBM

Brain tumours are the leading cause of cancer deaths in children, men under the age of 45 and women under the age of 25. Glioblastoma is the most common and most malignant primary tumour. The predominant treatment is surgical removal of the…

UK P3BEP

Germ cell tumours of the testis are the most common malignancy affecting adolescent and young adult males in Australia and many other Western countries, with a disproportionally high amount of healthy life lost each year due to the early age at…

WIRE

Renal cell cancer (RCC) is the 7th commonest cancer in the UK (12,500 new cases/year) and the most lethal of the urological malignancies with a 50% 10-year survival when considering all patients. Vascular endothelial growth factor (VEGF) tyrosine…