Treating newly-diagnosed patients with advanced therapy leads to dramatic improvements in outcomes.
A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.
The PROFILE trial was sponsored by Cambridge University Hospitals (CUH) NHS Foundation Trust and the University of Cambridge. It recruited from 40 hospitals across the UK. The results are published in The Lancet Gastroenterology and Hepatology.
For more information visit: CBRC The Lancet Gastroenterology and Hepatology
Published February 22 2024
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